TL1A/TNFSF15 Protein 1896-TL-010 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTL1A/TNFSF15 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number1896-TL-010
SpeciesMouse
Molecule NameTL1A/TNFSF15
Source/Expression SystemE. coli-derived Recombinant Mouse TL1A/TNFSF15 Protein
Quantity10 ug
NCBI Full Gene Nametumor necrosis factor (ligand) superfamily, member 15
NCBI Gene AliasesTl1, Tl1a, Tnlg1b, Vegi
FormatLyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular Weight20 kDa
Brand/TrademarkR&D Systems, a Bio-Techne Brand
ApplicationsBioactivity
Conjugate/TagUnconjugated
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Available conjugates: Unconjugated

614 McKinley Place N.E.

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United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

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(1) Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivoScientific reportsOctober 23, 2020Jacob N, Kumagai K, Abraham JP, Shimodaira Y, Ye Y, Luu J, Blackwood AY, Castanon SL, Stamps DT, Thomas LS, et al.

(2) Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiomeMucosal immunologySeptember 1, 2018Jacob N, Jacobs JP, Kumagai K, Ha CWY, Kanazawa Y, Lagishetty V, Altmayer K, Hamill AM, Von Arx A, Sartor RB, et al.

(3) Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune CellsJournal of immunology (Baltimore, Md. : 1950)February 15, 2018Ferdinand JR, Richard AC, Meylan F, Al-Shamkhani A, Siegel RM.

(4) Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cellsNature communicationsAugust 5, 2016Zhao Y, Chu X, Chen J, Wang Y, Gao S, Jiang Y, Zhu X, Tan G, Zhao W, Yi H, et al.

(5) A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and InfectionJournal of immunology (Baltimore, Md. : 1950)July 1, 2016Jia LG, Bamias G, Arseneau KO, Burkly LC, Wang EC, Gruszka D, Pizarro TT, Cominelli F.

(7) Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4Nature communicationsMarch 3, 2016Gomez-Rodriguez J, Meylan F, Handon R, Hayes ET, Anderson SM, Kirby MR, Siegel RM, Schwartzberg PL.

(8) CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22The Journal of experimental medicineJuly 28, 2014Longman RS, Diehl GE, Victorio DA, Huh JR, Galan C, Miraldi ER, Swaminath A, Bonneau R, Scherl EJ, Littman DR.

(9) TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriersMucosal immunologyMay 1, 2014Yu X, Pappu R, Ramirez-Carrozzi V, Ota N, Caplazi P, Zhang J, Yan D, Xu M, Lee WP, Grogan JL.

(11) The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4⁺ and CD8⁺ T-cell immunityFASEB journal : official publication of the Federation of American Societies for Experimental BiologyAugust 1, 2012Twohig JP, Marsden M, Cuff SM, Ferdinand JR, Gallimore AM, Perks WV, Al-Shamkhani A, Humphreys IR, Wang EC.

(12) Regulation of innate CD8+ T-cell activation mediated by cytokinesProceedings of the National Academy of Sciences of the United States of AmericaJune 19, 2012Freeman BE, Hammarlund E, Raué HP, Slifka MK.

(13) Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferationFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJanuary 1, 2011Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, et al.

(14) TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvantBiochemical and biophysical research communicationsJuly 3, 2009Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, Yoshikawa T, Hiroi T, Itoh N, Kawai Y, et al.

(16) Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissuesImmunologyJune 1, 2008Kim MY, Rossi S, Withers D, McConnell F, Toellner KM, Gaspal F, Jenkinson E, Anderson G, Lane PJ.

TL1A/TNFSF15 Protein from R&D Systems, a Bio-Techne Brand